(3) HLA TYPES IN RHEUMATIC DISEASE
نویسندگان
چکیده
منابع مشابه
HLA system and rheumatic disease.
Over 50 HLA antigens are now recognisable. Since we each have four antigens there are millions of possible combinations that characterise us as individuals. In humans these antigens are coded for in the major histocompatibility complex on the sixth chromosome. The loci for three of the complement components (C2, C4, and factor B) are in or near the major histocompatibility complex. In mice and ...
متن کاملImmunologic Factors in Acute Rheumatic Fever Compared to Rheumatic Heart Disease
Background/Objective: To clarify the state of different immunologic factors in patients with acute rheumatic fever (ARF) and rheumatic heart disease (RHD) compared to healthy individuals.Patients and Methods: Patients with ARF (#21), patients with RHD six months after the onset of ARF (#19), and healthy children from the same age group with normal physical examination and no history of pharyngi...
متن کاملHLA, autoimmunity, and rheumatic heart disease. Apparent or real associations?
T he report of Ozkan et all in this issue of Circulation identifies HLA allelic associations with rheumatic heart disease (RHD) in a Turkish population, a population previously untested for HLA associations with RHD. Of interest, they report a significantly increased expression of B16, DR3, and DR7 in their patient sample. The increased expression of DR3 and DR7 alleles observed in their patien...
متن کاملTakayasu's disease in two brothers. Analysis of HLA types.
Recent studies indicate that certain haplotypes of HLA are frequently associated with Takayasu's disease, and that HLA-A and B loci could determine the predisposition to this disease, especially in women. Ths paper describes two male sibs with Takayasu's disease in whom HLA typing was carried out. In addition, HLA types were determined on A, B, C, and DR loci of all family members. It was found...
متن کاملRheumatic Fever and the HLA Complex
Background Considering the controversial results published in the literature concerning associations between human leukocyte antigens (HLA) and rheumatic fever (RF), the purpose of the present study was to investigate by means of cosegregation analysis the participation of HLA genes in susceptibility to RF. Methods and Resuls The sample reported here was composed of 51 affected and 66 healthy i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 1979
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.68.1391